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A study conducted to find the results to on offensive topics such as the role of medication in the depression cases. The study concluded that antidepressants actually help to reduce the depression level. Some antidepressants are more effective and have better capacity than others. The study was conducted by approx. 530 trials on more than 1.10 lakh patients and about 21 antidepressants were examined.

Dr. John Ioannidis, a professor of Stanford University in California and one of the researcher said that for acute depression, antidepressants were working effectively. He also added that the drugs offer benefits however, it is not a permanent cure for depression. This statement clears that we need more effective drugs.

The most drugs that work more effectively as antidepressants and available in the US include Amitriptyline, Lexapro (escitalopram), Effexor (venlafaxine), Paxil (paroxetine), Trintellix (vortioxetine), and Remeron (mirtazapine). Also, there are some drugs that effects on rare patients, including Luvox, Prozac, and Oleptro. In the list of less tolerated drugs includes Cymbalta, Effexor, Luvox, Anafranil, and Amitriptyline.

The list of the most tolerable drugs includes Lexapro, Prozac, Trintellix, Celexa, and Zoloft. The study also suggests that there is prolonged debate regarding concern towards antidepressants efficiency due to its short-term benefits on the average and minimum level of depression and long-term benefits or side effects are studied in this research.

However, many of researchers have a different opinion on this, as they say, this study claims that all the medications are effective in treating depression. He added that all the dummy and less effective drugs should be classified as they are not the permanent solution. Depression is the disease that is hard to get a good medication as a permanent therapy. If it is hard to find a fair alternative, then it is preferable to use as a medication. From the view of both the researchers, the study looked at responses within eight weeks of treatment. However, these treatments will be for the longer duration.

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